Preparation of Surfactant-free Linear and Star-shaped Poly(L-lactide)-b-methoxy Polyethylene Glycol Nanoparticles for Drug Delivery

Biodegradable nanoparticles of methoxy poly(ethylene glycol)-b-poly( d, l-lactide)/methoxy poly(ethylene glycol)- b-poly(ϵ-caprolactone) blends for drug delivery

The effects of blend weight ratio and polyester block length of methoxy poly(ethylene glycol)-b-poly( d, l-lactide) (MPEG- b-PDLL)/methoxy poly(ethylene glycol)- b-poly(ϵ-caprolactone) (MPEG- b-PCL) blends on nanoparticle characteristics and drug release behaviors were evaluated. The blend nanoparticles were prepared by nanoprecipitation method for controlled release of a poorly water-soluble m...

Preparation of Star-Shaped Polylactic Acid Drug Carrier Nanoparticles

Drug carrier biocompatible and biodegradable nanoparticles of about 15 nm were prepared by solvent evaporation technique from star-shaped poly(D,L-lactide) synthesized using dipentaerythritol as core and Tin (II) ethylhexanoate as catalyst.

Self-assembling methoxypoly(ethylene glycol)-b-poly(carbonate-co-L-lactide) block copolymers for drug delivery.

Bicalutamide is the most widely used non-steroidal antiandrogen for treating early stage prostate cancer, but suffers variable oral absorption due to its limited aqueous solubility. Thus, our objective was to synthesize novel biodegradable copolymers for the systemic micellar delivery of bicalutamide. Flory-Huggins interaction parameter (cFH) was used to assess compatibility between bicalutamid...

Magnetite nanoparticles coated with methoxy polyethylene glycol as an efficient adsorbent of diazinon pesticide from water

Methoxy polyethylene glycol modified magnetite nanoparticles (PEGMNs) were synthesized and characterized by scanning electron microscopy (SEM), vibrating sample magnetometer (VSM), and X-ray diffraction (XRD). The adsorption of diazinon onto PEGMNs was investigated by UV-Vis spectrophotometry at 236 nm, through batch experiments. The effects of adsorbent dosage, solution pH, contact time, solut...

preparation and characterization of tri-block poly(lactide)- poly(ethylene glycol)- poly (lactide) nanoparticles for sustained release of rivastigmine